News: Surf Therapeutics Announces Early Feasibility Study (EFS) To Advance Non-Invasive Approach to Neuromodulation for Rheumatoid Arthritis

Surf Therapeutics, a clinical-stage neuro-immunomodulation company developing non-invasive ultrasound therapy for chronic inflammatory diseases, is announcing the start of an Early Feasibility Study evaluating its investigational ultrasound device in people living with rheumatoid arthritis. The study is designed to assess a non-invasive approach to activate a neural pathway that triggers a robust anti-inflammatory response, without

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News: Prana Surgical Completes First Clinical Procedures Using the Prana System™ in Early Feasibility Study

Prana Surgical, a Houston-based medical device company, today announced the completion of the first five clinical procedures using the Prana System™ as part of its early feasibility study in Australia. The Prana System™ has been developed to enable image-guided, minimally invasive surgery, conserving healthy tissue and driving personalized treatment plans in a range of conditions,

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News: Cadwell and Medical Informatics Corp. Announce Partnership to Bring Neurodiagnostic Data into Clinical Intelligence Ecosystem

Cadwell, a global leader in neurodiagnostic and monitoring solutions, and Medical Informatics Corp (MIC), creators of the Sickbay Clinical Platform, today announced a strategic partnership that aims to bring a new standard of integrated data and monitoring to hospitals. As part of the agreement, Cadwell systems will be the first neurodiagnostic product integrated with Sickbay’s

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News: Fisher-Titus Medical Center and Luma Health Partner to Improve Healthcare Access for Patients in Northern Ohio

With consumer-grade self-scheduling, waitlist offers, and more, patients have easier access to world-class care close to home. Fisher-Titus Medical Center, a leading local health system offering the full continuum of care services to more than 70,000 patients in northern Ohio, deployed the Luma Health platform across 17 departments and multiple service lines to provide more

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News: Motif Neurotech Launches Patient Registry for Future Research Opportunities

Motif Neurotech, a brain-computer interface (BCI) company developing technologies for mental health, today announced that its patient registry is now live and accepting submissions from individuals with treatment-resistant depression (TRD) who may be interested in learning about potential future research opportunities. The registry will collect contact information from interested individuals to gauge interest in future

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News: March Biosciences Receives FDA Regenerative Medicine Advanced Therapy (RMAT) Designation for MB-105 in Relapsed/Refractory CD5-Positive T-Cell Lymphoma

March Biosciences (March Bio), a clinical stage biotechnology company developing cell therapies for hard-to-treat cancers, today announced that the U.S. Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to MB-105, the Company’s first-in-class autologous CD5-targeted CAR-T cell therapy, in development for relapsed/refractory CD5-positive T-cell lymphoma. The RMAT designation was granted

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News: 6 female-founded startups shaping the Houston innovation ecosystem

This article from InnovationMap highlights the finalists for the 2025 Houston Innovation Awards, celebrating women-led startups driving impact across Houston’s innovation ecosystem, including March Biosciences, a TMC Venture Fund portfolio company, and Bairitone Health, a spinout from TMC’s Biodesign program, both recognized for their groundbreaking work in health technology and cancer therapeutics.

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News: Houston digital health platform Koda closes $7 million funding round

Houston-based Koda Health, a digital advance care planning company born out of TMC’s Biodesign Fellowship, has closed an oversubscribed $7 million Series A round led by Evidenced to scale its operations and expand its national reach. The funding follows a year of major growth and integrations, positioning Koda to bring goal-aligned care to millions more

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Careers: Babyscripts

Babyscripts is the best-in-class risk detection platform to drive better clinical decision-making and care for moms anytime, anywhere.

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Careers: Deep6ai

Deep 6 AI is the leader in precision research software, connecting all research stakeholders in an AI-powered, real-time ecosystem.

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Advisory Board

We bring together leaders within the Houston life science and healthcare ecosystem to help startups activate and access opportunities within the Texas Medical Center.

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News: The Top 25 Digital Health Companies of 2025

The Healthcare Technology Report is pleased to present The Top 25 Digital Health Companies of 2025. Global digital health investment in 2024 was more than $25 billion, and adoption rates are higher than ever: a recent Cleveland Clinic survey showed that 50% of Americans use at least one form of health-related monitoring technology. Against that

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Portfolio: Alleviant

Alleviant Medical is focused on developing a novel minimally-invasive device to treat congestive heart failure. Our proprietary technology is designed to relieve heart failure symptoms, improve quality of life, and reduce hospital admissions for over 16 million patients currently suffering from this disease in the US and EU.

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William F. McKeon

William McKeon is the President and Chief Executive Officer of the Texas Medical Center (TMC), the largest medical complex in the world. TMC is comprised of 60+ institutions, 120,000 employees, and an annual GDP of over $22 Billion. He is responsible for driving strategic, operational, and innovation initiatives to further TMC’s position as a global

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Portfolio: Babyscripts

Babyscripts’ market-leading pregnancy app is your digital front door to engage and remotely monitor pregnant & postpartum patients.

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Thomas Luby, PhD

Tom Luby Ph.D. is the Chief Innovation Officer of the Texas Medical Center (TMC) Innovation. In this role, he oversees all of the innovation efforts of TMC focused on research, education, and commercialization of novel healthcare solutions. Prior to this, he was the head of JLABS @ TMC in Houston, Texas. In that role, he

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Portfolio: Briteseed

Briteseed is commercializing a new class of smart surgical tools that have artificial-vision assistance to help surgeons quickly identify landmarks and safely navigate vital structures. These multifunctional tools have the benefit of cautery, dissection, and optical tissue sensing in a single package.

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Marcus Nelson

Marcus Nelson is the Vice President of Business Analytics at Texas Medical Center (TMC). In this role, he oversees all diligence for the TMC Venture Fund and leads strategic analyses for top initiatives. Marcus joined the Texas Medical Center in 2022. Marcus previously served as the Director of Strategy and Business Operations at a logistics

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Portfolio: Clarium

Clarium is building the next-gen supply chain platform that healthcare needs now. We proactively manage supply disruptions, identify substitutes, forecast surgical demand, optimize inventory planning and eliminate match exceptions ever-present in our volatile era. Our AI-enabled workflow and data tools are dramatically enhancing productivity for healthcare staff at forward-thinking institutions. All so they can focus

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Billy Cohn, PhD

Dr. Cohn is the Director for the Center of Device Innovation at the Texas Medical Center (TMC). He is also a professor of surgery at Baylor College of Medicine and an adjunct professor of Bioengineering at Rice University, the University of Houston and Texas A&M. Prior to joining TMC, he served as a Vice President

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Portfolio: CNSDose

CNSDose uses advanced genetic technology to fast-track finding the right antidepressant and dose. Genetically guided prescribing via CNSDose results in a 2.5 times greater likelihood of remission, which means faster recovery, reducing suffering and cutting costs that result from trial-and-error prescribing.

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Emily Reiser, PhD

Dr. Emily Reiser is the Director of Strategy and New Ventures, spearheading the Accelerators for Cancer Therapeutics, Healthtech, and international BioBridge programs. Since joining TMC in 2019, she transitioned from direct engagement with startup founders to overseeing a vast stakeholder network and now leading the recruitment of entrepreneurs in residence. Prior to joining TMC, Emily

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Portfolio: CorInnova

CorInnova is developing a soft robotic heart assist device that gently squeezes the heart in synchrony with the heartbeat to increase output. Delivered minimally invasively, the device is designed to bring a new paradigm of treatment to the 95 percent of heart failure patients who are ineligible for existing cardiac devices.

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Gabrielle Guttman

Gabrielle Guttman is the Associate Director of Strategy and New Ventures. In this role, she helps drive TMC’s strategic projects, including the Center for Device Innovation, as well as being an active member of the TMC Venture Fund. Prior to this, she worked at Johnson and Johnson Innovation as a Business Operations Manager at JLABS

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Portfolio: Crossbridge Bio

CrossBridge Bio is pioneering an approach to deliver the next generation of stable antibody-drug conjugates (ADC) therapeutics that carry dual payloads as targeted treatments for a range of challenging cancers. CrossBridge Bio’s headquarters are in Houston, TX, within the Texas Medical Center’s life sciences ecosystem.

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Portfolio: Deep 6 AI | Tempus

Deep 6 AI finds more, better matching patients for clinical trials in minutes rather than months by using artificial intelligence on clinical data. Full details on the 2025 acquisition here.

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Portfolio: Hamilton Health Box

Hamilton Health Box is the value-based primary care microclinic leader. HHB’s microclinic operating system leverages a hybrid primary care model to make healthcare accessible, convenient, and affordable for small footprint populations including small employers and rural populations. We aim to create healthier communities and reduce the total cost of healthcare through our high-touch primary care

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Portfolio: Ictero Medical

At Ictero Medical, we are developing the CholeSafe System, the first minimally invasive treatment option that helps decrease complications and costs while providing definitive therapy to high risk surgical patients with gallstone disease. Unlike laparoscopic cholecystectomy, the CholeSafe System can be used in the interventional radiology suite with only minimal local anesthesia to defunctionalize the

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Portfolio: Intelligent Implants

Intelligent Implants is a bioelectronics company developing a revolutionary electrical stimulation platform technology that is incorporated into standard-of-care orthopedic implants. Its first product, SmartFuse, represents a novel method of delivering electric current to aid spinal fusion that can induce, direct, and monitor bone growth in real-time.

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Portfolio: Koda Health

At Koda Health, we’re using AI to help guide difficult conversations in between providers and their elderly patients, starting with end-of-life healthcare.

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Portfolio: Lena Health

Lena Health enables health systems and payers to scale care coordination and navigation support to patients who need it most, improving access to care and social resources within their own community. Lena Health does this through a telephonic AI care coordinator that can coordinate with patients, clinics, pharmacies, insurers, and community-based organizations.

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Portfolio: Lifelet Medical

Lifelet Medical is developing a novel biomimetic leaflet material for heart valve replacements, transcending the durability and manufacturing limitations associated with current technology offerings.

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Portfolio: Luma Health

LumaHealth’s cloud-based platform empowers healthcare providers with HIPAA-compliant, mobile-first SMS and secure chat communication tools that enable frictionless patient-provider conversations — including intelligent scheduling, referral management, actionable reminders, and care pathway messaging.

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Portfolio: March Biosciences

March Biosciences, Inc is a clinical-stage cell therapy company with a mission to transform patient care in the most challenging hematological malignancies. March Bio’s lead asset is at the end of Phase I trials for T-cell malignancies, diseases with a dismal prognosis that is currently unaddressed by CAR-T and targeted therapy technologies. The company’s pipeline

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Portfolio: Medable

Medable is transforming healthcare by providing an enterprise platform for “Direct-to-Patient” clinical care and clinical trials, enabling patient generated data to drive healthcare delivery, research, and personalized and predictive medicine.

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Portfolio: Medical Informatics Corp.

MIC is a software company that provides real time patient monitoring and predictive analytics across the continuum of care in the hospital. Its innovative SickbayTM platform archives, aggregates, and transforms short-lived, high-resolution waveform data across disparate devices to enable anywhere, anytime remote monitoring. MIC applies machine learning to develop predictive algorithms, laying the groundwork for

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Portfolio: Motif Neurotech

Motif Neurotech is powered by innovations in efficient wireless power and data, unlocking possibilities for new, miniature implants for tissue stimulation and diagnostic readings.

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Portfolio: NarrativeDx | Press Ganey

NarrativeDx uses AI to identify actionable insights from patient and provider feedback that improves patient satisfaction scores, increases operational efficiency and decreases employee turnover. Full details on the 2020 acquisition  here.

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Portfolio: Noninvasix

Noninvasix will be the first company to non-invasively monitor the severity of sepsis and septic shock, enabling clinicians to diagnose and monitor the response to treatment of tissue hypoxia in real-time. Noninvasix’s patented optoacoustic platform technology is the first solution to non-invasively and continuously measure central venous saturation. Incorporating Noninvasix into the ICU workflow allows

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Portfolio: Path EX, Inc.

PATH EX, Inc. is focused on advancing a medical device that addresses an urgent unmet need. The company’s experienced team and institutional backing, combined with strong clinical evidence, represent an exciting breakthrough in the fight against sepsis.

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Portfolio: Sonavex

Sonavex’s two FDA approved products, EchoMark and EchoSure, enable ultrasound based vascular monitoring to detect flow compromises earlier.

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Portfolio: Venostent

We’re a clinical-stage therapeutic medical device company that’s developed finely-tuned, bioabsorbable wraps intended to improve outcomes for the 5 million vascular surgeries performed each year.

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Portfolio: Vivifi Medical

Vivifi Medical has developed the first suture-less laparoscopic technology that enables the connection of two vessels together for the treatment of Varicocele & Men’s Health Issues.

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Portfolio: Volumetric | 3D Systems

Volumetric Biotechnologies is focused on innovations in volumetric imaging and biotechnology, such as 3D imaging, bioprinting, tissue engineering, or other fields reliant on volumetric data. Full details on the 2021 acquisition here.

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